Pregabalin

Gabapentin Information for Health Professionals

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FDA is warning that serious, life-threatening, and fatal respiratory depression has been reported with the gabapentinoids, gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR). Most cases occurred in association with co-administered central nervous system (CNS) depressants, especially opioids, in the setting of underlying respiratory impairment, or in the elderly. Our evaluation of respiratory depression … Read more

Difference Between Pregabalin and Gabapentin

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While gabapentin (Neurontin) and pregabalin (Lyrica) share many similarities, there are a few things that set them apart. We’ll highlight seven key differences between these medications below. 1. Pregabalin is FDA approved for more uses than gabapentin, but both are often used off-label Pregabalin and gabapentin are both FDA approved as an add-on treatment for partial-onset seizures. But pregabalin … Read more