There haven’t been enough strong clinical studies looking at Fioricet and its effects on pregnancy, so it’s not completely known how safe it is during pregnancy.
A study found that Fioricet could potentially raise the risk of heart problems in unborn babies. In addition, there has been a report of a newborn experiencing withdrawal seizures at birth. This is likely related to the fact the mother took a medication with butalbital during the last two months of pregnancy. If you’re pregnant or planning on becoming pregnant, discuss the risks and benefits of using Fioricet with your provider.
Ingredient Analysis
- Butalbital:
- Risk: As a barbiturate, it may cause birth defects, fetal dependence, or withdrawal symptoms in the baby if used for prolonged periods or in high doses.
- FDA Pregnancy Category: Previously classified as Category C (risk cannot be ruled out), meaning animal studies have shown adverse effects, but adequate human studies are lacking.
- Acetaminophen:
- Risk: Generally considered safe for occasional use during pregnancy, but recent studies suggest that excessive or prolonged use may be linked to developmental issues or ADHD-like symptoms in children.
- Safe dosing is critical to avoid liver toxicity, especially in pregnancy.
- Caffeine:
- Risk: High caffeine intake during pregnancy has been associated with a higher risk of miscarriage or low birth weight. The caffeine content in Fioricet is relatively low (40 mg per tablet), but it contributes to your overall daily caffeine intake.